KMOV St. Louis — News
05/11/2026 08:42

2 dead after wrong-way crash on westbound I-64 in Frontenac

FRONTENAC, Mo. (First Alert 4) - Two people died after a wrong-way crash involving three vehicles on Interstate 64 on Wednesday night.

The crash occurred on westbound Interstate 64 east of North Ballas Road in Frontenac around 9:30 p.m.

According to a crash report from the Missouri State Highway Patrol, a 25-year-old woman was driving a midsize car in the wrong direction in the westbound lanes.

The woman crashed head-on into a 30-year-old man driving a luxury car. A third car then rear-ended the 30-year-old driver’s car.

Paramedics pronounced both the woman and the man dead at the scene, according to the report. The third driver was uninjured.

Road crews temporarily closed all westbound lanes for several hours while they cleared the scene.

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